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Aim 1
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Develop new systems-level approaches, tools and applications to understanding biological complexity from the perspective of hierarchies of molecular and cellular networks that relay information and give rise to emergent behavior. The reality of biological systems is that there is a dynamic interplay between molecular networks that leads to complex phenotypes. Transitions between states are also mediated by molecular networks. Understanding these transitions is the central focus of Aim 1. Although gene regulatory networks, signaling networks, or metabolic networks tend to be studied one network at a time, a systems view of biology demands that we measure and model the dynamic interplay among the hierarchy of molecular networks to make predictions.
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Institute for Systems Biology
CSB Home
Center for Systems Biology at the Institute for Systems Biology
