To develop core facilities that serve as venues for collaborative technology development, implementation and application in a variety of biological systems.

Core technology and platform development are driven by the increasing biological complexity of the research programs. The tools, functionality and data developed in Aim 2, the research programs, are expanded to apply to organisms of increasing complexity. As these tools and technologies become mature, the Center makes them freely available for public use through the ISB website http://www.systemsbiology.org/Resources_and_Development. We strongly encourage public availability, use and dissemination of our tools and data sets.

The four Cores: Informatics, Microfluidics and Imaging, Proteomics, and Genomics, house both mature, or high throughput, and emerging technologies. Mature Cores are self sufficient and operate on a fee-for-service basis. For emerging technologies to be released as mature: Core capabilities are developed and stabilized in tandem with the most amenable experimental system(s) and applied to systems of increasing complexity. Education/training are first completed internally and then provided to the community as an educational course (through Aim 4). The Center has been critical for developing our Imaging and Microfluidics Core and has resulted in leveraged equipment that has significantly increased the Core s capabilities. Each Core is managed by expert personnel and has a designated  go to person to provide training or assistance during research projects. The scheduling of all Core resources is centralized through an internal on-line system.