Center for Systems Biology (CSB)


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	Core Facilities

		Genomics Core

		Proteomics Core

		Microfluidics and Imaging Core

		Informatics Core


	Resources


		Publicly Available Resources All Center generated resources are publicly available. Informatics Core Research Informatics software Computational Biology Research group software ISB downloadable software ISB downloadable data sets Core Facilities: Center technology development is driven by the increasing biological complexity of scientific inquiry. Each Core is a venue for collaborative technology development and application in a variety of biological systems. The NIGMS award has been critical for catalyzing the development of the Informatics and Microfluidics and Imaging Cores and is the foundation for Core outreach, education and training. Leverage of the NIGMS award with another NIH program resulted in the acquisition of a Laser-enabled analysis and processing (LEAP) instrument that provides significantly higher throughput and more targeted perturbation of cell populations. The LEAP acquisition has resulted in new research capabilities and educational and training opportunities made possible solely by the NIGMS award. Genomics Core The Genomics Core provides microarray-based technologies measuring genomic expression and protein-DNA interactions. More Proteomics Core The Proteomics Core provides state-of-the-art mass spectrometry-(MS)-based technologies for obtaining accurate, comprehensive, and dynamic information about proteomes, sub-proteomes, post-translational modifications and individual proteins. More Microfluidics and Imaging Core The Microfluidics and Imaging Core forms the nexus of a collaborative effort to perform high-throughput multiplexed measurements of live cells including Halobacteria, yeast and cells derived from mammalian systems based on multiparameter analysis of optical phenotypes and optically active reagents. Our objective is to create an interdisciplinary incubator dedicated to developing new technology platforms or experimental methodologies systems-based approaches to study single cells. More Informatics Core The Informatics Core provides a computational infrastructure that enables scientists to work in the way they want, have access to the data they require and perform analyses they need. Therefore, the Core has adopted the most applicable practices of industrial software development and the creativity of research-lead innovations. More

Publicly Available Resources

Core Facilities: